Comparative Genomic Analysis of Two Multidrug-Resistant Clinical Isolates of ST395 Epidemic Strain of Pseudomonas aeruginosa Obtained 12 Years Apart
نویسندگان
چکیده
Pseudomonas aeruginosa can cause large and prolonged outbreaks in hospitals. We have sequenced and annotated the genomes of two multidrug-resistant P. aeruginosa isolates from the same strain obtained 12 years apart from different patients. Genomic analysis provided insight on the genes acquired and lost by P. aeruginosa during its spread.
منابع مشابه
Genomic characterization of a local epidemic Pseudomonas aeruginosa reveals specific features of the widespread clone ST395
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen with several clones being frequently associated with outbreaks in hospital settings. ST395 is among these so-called 'international' clones. We aimed here to define the biological features that could have helped the implantation and spread of the clone ST395 in hospital settings. The complete genome of a multidrug resistant index isol...
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2014